Do you have any advice when utilizing palliative radiation therapy in patients currently being treated with a PARP inhibitor?
Can the drug continue during radiation therapy or should it be discontinued at a specified time prior to initiation of radiation?
Answer from: Radiation Oncologist at Academic Institution
This is an excellent question and certainly will become more of an issue with the recent FDA approval of olaparib for HR-defective (HRD) metastatic ovarian cancer. In addition, many other HRD metastatic cancers are being treated with this drug under compassionate use. Furthermore, the recent Ph...