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Topics:
Psychiatry • General Psychiatry
Do you modify dosing or use of bupropion to mitigate seizure risk in patients without eating disorder who are restricting calories to lose weight?
Do you worry about additional increased risk of seizure for patients using medications to assist in weight loss such as GLP-1 agonists?
Answer from: at Academic Institution
No. The risk of seizures with bupropion is 0.1% with daily doses below 300 mg and 0.4% with doses up to 450 mg daily. The increased risk of seizures in eating disorders is due to higher risk of severe electrolyte disturbances that result from disordered eating, induced vomiting, and laxative abuse. ...
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