What are the most effective strategies for managing weight gain associated with antipsychotic medications?
Answer from: at Community Practice
In my experience, the following things have worked.
Reassurance that it is a medication side-effect.
Consider switching the anti-psychotic (or at least try and decrease the dose of the antipsychotic). Aripiprazole, Caplyta (Lumateperone), and Vraylar (Cariprazine) have shown benefits vis a vis w...
When counseling for lifestyle modification is insufficient, I've experienced with the four different medications:
Metformin - I've had the best results with this.
Topiramate - I've used it when there may be a benefit for comorbidity, such as migraines or binge eating disorder (I have had good lu...
Dietary consult to work on diet.
Metformin to help with glucose tolerance. Weight loss is very minimal but I like to use this in hopes that weight gain is minimal.
I have heard great results from using GLP-1 agonists and some patients lose 25-30 lbs especially clozapine where weight gain is very...
While I have had great results using Abilify in bipolar patients, it has been consistently a problem concerning weight gain. The increased "hunger" especially for sweets has caused almost all my patients to gain significant weight leading to poorer self-image and increased depression especially mark...