When do you choose to switch to antidepressants vs augmentation in treatment-resistant depression?
Answer from: at Academic Institution
When I approach depression that has been resistant to many antidepressant trials, I consider the following:
First, I reassess the diagnosis. This includes considering comorbidities such as menopause symptoms, ED symptoms, exacerbation of chronic medical issues, and onset of MNCD. I ensure I have co...
Comments
at Comprehensive Psychological Services I agree with the above.
at Private Practice I would do the same and consider augmentation with...
at Legacy Community Health Thanks for this contribution!
at University of Oklahoma Health Science Center-College of Health Very thoughtful and comprehensive discussion, Dr. ...
at Kaiser Foundation Office Very thorough and good response!
at Los Alamos Psychiatry Associates Well thought out algorithm!
at Kirk Kerkorian School of Medicine at UNLV Agree overall. Great and detailed response
Treatment-resistant depression has been profoundly rare in my private practice over the past 34 years. Most patients with the diagnosis of treatment-resistant depression that I see aren't really depressed. They have a pessimistic explanatory style which doesn't respond to any medications. If they do...
Comments
at Private Practice That's a super interesting and refreshing comment....
at Los Alamos Psychiatry Associates I especially see a lot of missed bipolar with my p...
at Chen And Pinard Medical Group
The overwhelming majorit...
If the first antidepressant at full therapeutic doses, and after sufficient time to maximize its efficacy, has shown partial benefit, I would most likely not taper and stop it, but rather use a second-generation antipsychotic medication.
If, however, I thought there could be some elements of bipola...
Treatment-resistant depression is an interesting condition. I would first do a thorough interview, get extensive collateral, and try to do a good differential before thinking about treatment options. Is this TRD or undiagnosed bipolar depression or bipolar 1 or 2 starting as depression before having...
Comments
at Tewksbury Hospital Exactly! I am wondering why the majority of respon...
at Santuary For Healing And Integration In my opinion, adding a second antidepressant to a...
at Banks And Sood Mds Use an antidepressant from a different class. ...
I agree with the above.
I would do the same and consider augmentation with...
Thanks for this contribution!
Very thoughtful and comprehensive discussion, Dr. ...
Very thorough and good response!
Well thought out algorithm!
Agree overall. Great and detailed response