Do you offer adjuvant androgen deprivation therapy for AR+ salivary ductal carcinomas treated with curative intent?
If so, how do you sequence it? Would you consider before adjuvant radiation vs concurrent with adjuvant (chemo)radiation vs after adjuvant radiation? How long do you give ADT for? Do you follow the prostate cancer protocols?
Answer from: Radiation Oncologist at Academic Institution
There is a recently released ASCO guideline [Geiger et al., PMID 33900808] which specifically addresses the role of systemic therapy in the management of salivary gland malignancies.Regarding systemic therapy, the recent ASCO guideline suggests concurrent chemotherapy, HER2-Neu targeted therapies, a...