Do you offer neoadjuvant radiation therapy for oral cavity sarcoma?
If so, what dose/fractionation?
Pathology: High grade spindle cell sarcoma
Answer from: Radiation Oncologist at Academic Institution
Rare situation. Be sure the path is unequivocal (and not e.g., a sarcomatoid SCC, which is not at all a sarcoma). If it really is a sarcoma, preop (50 Gy/25 fx with sarcoma expansions) is reasonable if your surgeon is comfortable with it, but oftentimes there is less familiarity/comfort with preop R...
Answer from: Radiation Oncologist at Academic Institution
This is where a multidisciplinary tumor board can be helpful because you want to make sure your H&N surgeons are comfortable with operating after radiation before proceeding down that route. Since pre-op RT is done so infrequently for H&N cancers, some ENTs may not want to try it.