Do you prefer using losartan in your patients with hypertension and gout due to its uricosuric effects?
Answer from: at Community Practice
I do find losartan helpful. It is especially helpful asking a PCP to change HCTZ to losartan.
Though the losartan's urate-lowering effect is a small amount, I combine this with dietary changes (especially greatly limiting the intake of foods high in fructose) and eating purines in moderation,...
After reading about the uricosuric effects of losartan in a NEJM review article on gout, I was excited to use losartan in patients with gout. However, over the years of following serum urate levels in my hypertension patients, I've noticed that losartan does not provide enough urate lowering to make...