Do you recommend adjuvant therapy for early stage (IB) high grade endometrial stromal sarcoma?  

Tanner et al., PMID 22750260 demonstrated that these cancers have an exceptionally poor prognosis. Since there are no randomized trials, utilization of both adjuvant radiotherapy and chemotherapy with carboplatin/taxol or gemcitabine/taxotere would seem appropriate. As with endometrioid cancers of t...