Do you routinely treat patients with neurosyphilis with IM penicillin for 1-3 weeks after completing a full treatment course of IV penicillin?  

The same question was asked almost exactly two years ago. Repeating the same reply with minor edits: This has been a topic of a debate among syphilis experts for decades. There are no data at all on whether there is benefit (e.g. in preventing later relapse) in adding low-dose but long-acting penic...

I agree with everything written here by Dr. @Handsfield. At the risk of biasing the discussion, I'd like to add that one potential, purely logistical, system-dependent benefit of providing a dose of BPG at the end of the IV penicillin course is to create a touchpoint between a patient and the health...