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General Internal Medicine • Infectious Disease • General Infectious Disease • General Primary Care
What do you think about chronic suppressive therapy for HSV-2 in a patient with positive antibodies but no prior clinical outbreak?
Would you expect the presence of antibodies to indicate either immunity from contracting the infection, or otherwise risk of transmitting a latent infection?
Answer from: at Academic Institution
This patient was likely infected with HSV-2 in the past despite the absence of symptoms and may potentially infect a partner who is not immune; since viral shedding begins before symptoms, this is definitely a risk. I would have an informed consent discussion on possible transmission prevention with...
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