Do you use combination antibiotic therapy for treatment of bacterial endocarditis due to gram-negative bacilli?

The approach towards different might differ depending on whether the culprit organism belongs to the HACEK group or the nonHACEK group. The mortality rates per literature were approximately 2% for HACEK and 20-30% for the nonHACEK group.

Combination therapy is usually not recommended for HACEK endoc...