Do you use docetaxel interchangeably with paclitaxel in breast cancer?
Does the answer vary based on whether it is neo/adjuvant or metastatic setting?
Answer from: Medical Oncologist at Academic Institution
The nuanced answer would be attuned to receptors, disease status (e.g. non-metastatic vs metastatic) and schedule.In the adjuvant setting, defining studies include E1199 (Sparano et al JCO 2015) and S0221(Budd et al JCO 2015).
The ECOG trial examined weekly paclitaxel vs weekly docetaxel vs q3wk pac...