Does microscopic ENE warrant post-mastectomy radiotherapy if all other factors are low risk?

For example, in a patient with T1 disease and 1/1 node involved with a micromet and focal ENE.

Would your recommendation change if the patient were receiving chemotherapy?

Would you consider treating the lymph nodes alone to avoid reconstruction complications?

Answer from: Radiation Oncologist at Academic Institution

With respect to ENE, I first look at axillary surgery. If the patient has SLN+ and microscopic ENE, I do typically offer PMRT even with other low-risk factors. While the IBCSG trial evaluates micrometastases, it's important to remember 90% received lumpectomy, and therefore, most received whole brea...

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Radiation Oncologist at Mon Health
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Does microscopic ENE warrant post-mastectomy radiotherapy if all other factors are low risk?

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