Does the literature support a benefit for whole lung irradiation for high risk rhabdomyosarcoma with multiple lung metastases?   

My opinion is that there are no direct data. The European investigators are talking about doing a randomized study to investigate the value in intermediate risk patients. In US it has been standard for stage 4 pulmonary cases with RMS since WLI was established for patients with Ewings Sarcoma in IES...