Does the presence of an ATM mutation impact your fractionation regimen for a woman with breast cancer?

Answer from: Radiation Oncologist at Community Practice

ATM mutation is not a contraindication for RT. Techniques should be used to reduce scatter dose to contralateral breast. This is very good review on the topic.https://www.ncbi.nlm.nih.gov/pubmed/31381960

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Radiation Oncologist at Mount Auburn Hospital
Thanks so much for that great reference. I don't k...

Answer from: Radiation Oncologist at Academic Institution

Though not a lot of data, I have treated patients with hypofractionation (breast or breast and RNI) and not noticed any issues.

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Radiation Oncologist at Mallory Radiotherapy, PLLC
Anecdotally, I recently treated a large breasted w...

Radiation Oncologist at Varian Medical Systems/Allegheny health network
It could be a function of breast size as it is an ...

Radiation Oncologist at Mallory Radiotherapy, PLLC
Thanks. My patient had a different heterozygous mu...

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Does the presence of an ATM mutation impact your fractionation regimen for a woman with breast cancer?

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