For an otherwise resectable esophageal cancer with involved celiac lymph nodes, would you ever consider an SIB beyond 50.4 Gy?

Assuming duodenum constraints are met, could there be any benefit to boosting a positive celiac node to 61.6 Gy in 28 fractions?

Answer from: Radiation Oncologist at Community Practice

Intuitively, it seems like 50.4 Gy is not enough, as pathologic complete response rates are low. Based on multiple randomized trials, no dose higher than 50.4 Gy has been superior to 50.4 Gy for esophageal cancer. This included the primary tumor and grossly involved nodes. The NCCN now recommends s...

Comments

Radiation Oncologist at Mallory Radiotherapy, PLLC
I believe patients on ARTDECO (definitive cases) h...

Radiation Oncologist at Lake Huron Medical Center
I agree! We are using the exact same dose for defi...

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For an otherwise resectable esophageal cancer with involved celiac lymph nodes, would you ever consider an SIB beyond 50.4 Gy?

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