For colorectal cancer, would you consider using capecitabine 5 days on, 2 days off instead of the usual 2 weeks on, 1 week off or 1 week on, 1 week off schedules?

Aside from chemoradiation, are there situations in which you might consider this alternate schedule?

Answer from: Medical Oncologist at Academic Institution

The 14-day (q21d) schedule for cape was always difficult yet Roche did not wish to address it. The 7-day q14 day was an attempt to give a higher dose density, which is possible but not necessary. Personally, I use 7-day dosing frequently. Just as we do not need to give prolonged infusions of 5FU, pr...

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Medical Oncologist at Los Angeles VA Medical Center
Dr. @Howard Hochster, do you ever use metronomic c...

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For colorectal cancer, would you consider using capecitabine 5 days on, 2 days off instead of the usual 2 weeks on, 1 week off or 1 week on, 1 week off schedules?

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