Given RADICALS-HD, are you completing 24 mo vs 6 mo of ADT with XRT following RP?
RADICALS-HD trial (ESMO 2022) demonstrated metastasis free survival benefit with 24 months compared to 6 months of ADT.
Answer from: Radiation Oncologist at Community Practice
Initial: We know 2 years of ADT works. Adding to the classic RTOG 9601, RADICALS-HD demonstrated an improvement in the primary and clinically-relevant endpoint of MFS.Who should be offered 2 years is a more nuanced question. I rely heavily on the PSA to guide as I am influenced by the significant in...
Comments
Radiation Oncologist at Tennessee Oncology I too await the full manuscript, which I hope will...
Radiation Oncologist at Kansas City VA Medical Center I look at several prognostic factors, most importa...
Radiation Oncologist at Kansas City VA Medical Center Parker reported no meaningful difference among thr...
Answer from: Radiation Oncologist at Academic Institution
I very much struggle to make sense of what to do with RADICALS-HD since 43% of patients received RT in the adjuvant setting and most of them received RT to the prostate bed alone, both of which are no longer SOC (at least assuming PSA > 0.34 as per RTOG 0534). The 'standard' arm of 6 months would...
I too await the full manuscript, which I hope will...
I look at several prognostic factors, most importa...
Parker reported no meaningful difference among thr...