Given the MA20 results, do you consider CW plus SCV or even regional nodal radiation postmastectomy for pT3N0 with high risk features?  

I would certainly recommend PMRT for T3N0 with high-risk features (LVI, grade III, etc.). Actually, even before the MA 20 data is available, T3N) with LVI has a higher risk for LF as demonstrated in one of our papers (Floyd et al ). To avoid PMRT for T3N0, there should be no high-risk features (no g...

I would treat the s/c and IMN when PMRT is indicated for a T3N0 with high-risk features. The information in the literature regarding PMRT is to treat all or none, so once you give PMRT, it will include chest wall + regional LN's. We have published a paper on patients with 1-3 positive LN's receiving...