Given the sensitivity and prognostic value of the serum free light chain ratio for light chain multiple myeloma, do you continue to check urine studies?
Answer from: Medical Oncologist at Community Practice
This is a very pertinent and timely question. In fact, there is finally data. Dr. Dejoie et al published in Blood a study comparing the performance of serum and urine measurements in 113 newly diagnosed light chain myeloma patients. Interestingly only 64% of these patients had a measurable urine pr...
Agree with @Craig C. Hofmeister:
At this time the only good reasons to check Urine 24hr values are:
1. Identify people that may have albumiuria and nephrotic syndrome related to renal injury from a plasma cell mediated process.
2. For clinical trials where complete remissions need to be confirmed...