How do you approach a metastatic juvenile granulosa cell tumor of the ovary in a premenopausal patient following a hysterectomy and USO with the remaining ovary in situ?

Is there any role for completion surgery and/or RT in addition to chemotherapy?

12cm mass on ovary s/p TH/USO and preservation of grossly normal contralateral ovary. Peritoneal biopsies with two biopsy sites positive for malignancy. Cytology negative.

Answer from: at Academic Institution

In this patient who does not desire fertility (as she is s/p hysterectomy), I would recommend completion surgery with USO, omentectomy, removal of any residual peritoneal disease, assessment of lymph nodes and removal if abnormal. Would recommend platinum-based chemotherapy after surgery and reserve...

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How do you approach a metastatic juvenile granulosa cell tumor of the ovary in a premenopausal patient following a hysterectomy and USO with the remaining ovary in situ?

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