How do you approach chemotherapy dosing in extremely obese patients?
Does it differ in the curative vs palliative setting? Specifically thinking about adjuvant CAPOX in a patient with a BSA of 3. ~400 mg of oxaliplatin makes me a bit nervous.
Answer from: Medical Oncologist at Academic Institution
Our approach to chemotherapy dosing for overweight and obese patients remains as we recommended in JCO 2012 by Griggs et al., PMID 22473167. Most overweight and obese patients should be dosed with cancer chemotherapy based on their actual body weight/BSA and any dose reductions should be made as you...