How do you approach management of a young inflammatory breast cancer patient after a CR to neoadj chemo but refuses surgery?  

I would first review the NCDB study showing the best outcomes for trimodality therapy (Reuth et al). Then explore why. If it is a belief CR means cured highlight imaging can be discordant. There will often be cancer found at surgery. If there is a pCR that is the best chance for cure but even with t...