How do you approach managing depression symptoms in patients who have had repeated high risk of bleeding?

When do you determine SSRI therapy is unsafe to pursue in such situations?

Answer from: at Academic Institution

Overall, evidence suggests that while SSRIs do increase the risk of bleeding. The absolute risk of a bleeding event remains low and is usually not serious. A 2017 meta-analysis by Laporte et al., suggested that overall bleeding risk is increased by at least 36% while other meta-analyses suggest that...

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at Dale Rosin, D.O., LLC
Agreed.

Answer from: at Community Practice

Use vitamin C 500 mg TID. If minimal response, add vitamin K2 to the regimen to reduce the risks.

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How do you approach managing depression symptoms in patients who have had repeated high risk of bleeding?

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