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How do you approach systemic treatment for endometrial endometrioid adenocarcinoma with neuroendocrine differentiation?
In what situations would you use a neuroendocrine chemotherapy regimen over carboplatin+paclitaxel?
Answer from: at Community Practice
We treat these as endometrioid primary as the histologic diagnosis states, "endometrioid endometrial adenocarcinoma with neuroendocrine differentiation" instead of "primary neuroendocrine carcinoma of the uterus." Therefore, follow the literature from GOG 209 to support carboplatin/paclitaxel, ...
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Answer from: at Community Practice
Carbo or cis plus etoposide
Standard for NE tumors