How do you decide between ceftolozane/tazobactam and ceftazidime/avibactam for empiric treatment of an infection due to difficult-to-treat Pseudomonas aeruginosa while awaiting additional susceptibilities?
Answer from: at Academic Institution
Either is generally acceptable. The choice of empiric therapy in this circumstance may be dependent on additional information, if available. As an example, a patient with cystic fibrosis may have recent microbiological data that could guide the decision. Such information, however, is not often avail...
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at Stanford The results of the CACTUS study have just appeared...
Our institution prefers ceftolozone tazobactam for PSA rather than caz-avi. This is due to data shown above regarding higher rates of clinical success- since both are available to us, we prefer to avoid unnecessary use of caz-avi except for CRE. the only time we use caz avi for PSA is if the patient...
The results of the CACTUS study have just appeared...