How do you decide to transition a patient with stable PNH on eculizumab to extended half-life ravulizumab?

It is not complicated to do the eculizumab->ravulizumab transition. When the next dose of eculizumab is due, I just substitute ravulizumab. The first one is the loading dose and 2 weeks later, the maintenance dose. Following the first maintenance dose, the schedule is every 8 weeks.