How do you decide when to offer post-operative adjuvant treatment for a stage IC1 ovarian granulosa cell tumor?  

The postoperative management of stage IC granulosa cell tumor of the ovary remains controversial. In early-stage granulosa cell tumors, the major factors that have been studied in terms of risk of relapse have included tumor size, nuclear atypia, mitotic count, and rupture. Unfortunately, there is n...

This is an excellent question, and remains an area of active debate.  It is important to differentiate between adult-type and juvenile granulosa cell tumors, as this may impact treatment recommendations.  For patients with stage 1C1 adult type granulosa cell tumors both observation and che...