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How do you manage a FIGO stage IB dedifferentiated endometrial carcinoma that is MMR deficient and p53 wt?
Answer from: Radiation Oncologist at Community Practice
Aggressive disease. Favor chemo plus IO (MMR-d) (Van Gorp et al., PMID 39284383) followed by EBRT.
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Answer from: at Academic Institution
If this patient was adequately staged, I would proceed with a CT scan to try to find measurable disease. If there was measurable disease, I would give them chemo+IO per GY018 or RUBY. If there was no measurable disease, I would look harder for some and still if I couldn't find it I would give them p...