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How do you manage oxaliplatin-induced acute peripheral nerve hyperexcitability?
Patients can develop sensory and motor symptoms such as paresthesias, jaw/facial pain and stiffness, cramping and twitching, ptosis and vision changes, and throat discomfort and voice changes.
Answer from: Medical Oncologist at Academic Institution
This can be very frustrating for both the patient and the treating physician, as there is little that we can do to prevent this from happening. I have found that assurance is the most important thing that we can do for patients. For example, some patients can develop pharyngolaryngeal dysesthesias (...
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Answer from: Medical Oncologist at Community Practice
Anecdotally, in our practice, we had success with prolonging the oxaliplatin infusion time to 3 or 4 hours. Completely agree about irinotecan induced dysarthria mentioned by Dr. @Jason S. Starr.
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Medical Oncologist at Duke University
We have had the same experience in our practice. M...
We have had the same experience in our practice. M...