How do you manage patients with bilateral renal cell carcinomas?
What are the special considerations in the non-metastatic setting vs metastatic setting?
Answer from: Medical Oncologist at Academic Institution
Bilateral RCC without distant mets should be managed surgically if at all possible (e.g. bilateral partial nephrectomies), assuming adequate residual renal function. Pre-operative TKI to enable partial nephrectomy has been reported in multiple phase 2 trials with some success. If metastatic, then I ...