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How do you manage squamous cell carcinoma in situ of the anus?
While the Nigro/Wayne state regimen consisting of Mito C & 5FU is well stablished for squamous cell carcinoma of the anus/perianal tissue, are there any data for the management of patient with squamous cell carcinoma in situ of the anus/perianal tissue? Is the Mito C/5FU regimen applicable in a patient with squamous cell carcinoma in situ of the anus?
Answer from: Radiation Oncologist at Academic Institution
The first question I always ask when I get a case of in-situ squamous cancer is it reallly in-situ? If the physical examination suggests an invasive cancer or if the visible disease is very superficial but extensive, then it may be a sampling error and a few more biopsies are indicated.Assuming tha...
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