How do you manage systemic therapy with SRS for brain or spine metastases?
Do you routinely pause systemic therapy when administering SRS? Which agents do you view as relative or absolute contraindications with SRS?
Answer from: Radiation Oncologist at Academic Institution
This is an interesting and challenging question with limited data and a high degree of variability among providers. Thus clinical practice patterns and preferences vary even among our institution.
For Gamma knife/intracranial SRS, the range of time with immunotherapy and targeted agents varies at o...