How do you sequence HDR brachytherapy boost and external beam RT for prostate cancer?
Do you tend to do HDR before or after external beam? Is there more toxicity with one approach?
Answer from: Radiation Oncologist at Academic Institution
The typical sequence for our combination IMRT/HDR patients is IMRT first followed by the HDR boost about a week later. HDR is much more forgiving (substantially less GU toxicity) so the gap between IMRT and HDR is less than when we did seed boosts. However, our first clinical trials in the late 1990...
Answer from: Radiation Oncologist at Community Practice
I think either approach is acceptable. The THEPCA study has been presented in abstract form: https://ascopubs.org/doi/abs/10.1200/JCO.2021.39.6_suppl.236.Patients randomized to HDR boost either prior or after EBRT.No sig diff in GI/GU toxicities at 1 year. Will be nice to see the THEPCA st...
Comments
Radiation Oncologist at Penrose Cancer Center I typically prefer EBRT followed by HDR brachyther...
Radiation Oncologist at Prostate Cancer Center Of New Jersey We published our experience several times, both as...
Radiation Oncologist at Mosaic Life Care at St. Joseph I find the friability (and fragility) of tissues t...
Radiation Oncologist at UCSF Medical Center If the overall treatment time is similar, then I d...
Radiation Oncologist at South Florida Radiation Oncology I have performed both ways and in my experience, u...
Radiation Oncologist at UW Carbone Cancer Center From my experience 2003 onward, following closely ...