How do you think about management options in a patient with a minute focus of Gleason grade 4 (4+4) on 1 core from needle biopsy along with only Gleason 3+3 disease in other biopsy cores and PSA<10?

Assuming patient is not a surgical candidate and wishes to pursue definitive radiotherapy, what duration of ADT would you give?

Answer from: Medical Oncologist at Academic Institution

This patient has "Favorable High Risk Prostate Cancer", and has outcomes similar to an intermediate unfavorable risk patient, rather than a true high risk patient. See here.I would offer this patient at least 6 months of ADT with IMRT. It would not be wrong to offer a longer course of ADT (24 mo), b...

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How do you think about management options in a patient with a minute focus of Gleason grade 4 (4+4) on 1 core from needle biopsy along with only Gleason 3+3 disease in other biopsy cores and PSA<10?

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