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How do you treat a primary pineal neoplasm of intermediate differentiation?
Would extent of surgical resection matter?
Do these patients need CSI (like Pineoblastoma), just local radiation, or something in-between (say whole ventircular or whole brain + boost)?
Answer from: Radiation Oncologist at Academic Institution
Pineal parenchymal tumors of intermediate differentiation (PPTID) represent a rare type of intracranial tumor that behaves somewhere between pineocytomas and pineoblastomas. Given the rarity of PPTID, data is limited to retrospective studies with no clear consensus on adjuvant therapy. In general, a...
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Answer from: Radiation Oncologist at Academic Institution
I completely agree with Dr. @Tony J. Wang in that a multi-disciplinary discussion is critical when it comes to managing PPTID and given lack of prospective data there is no consensus (and probably there will never be given the rarity of this disease).Incidentally, in the past 3 months, our clinic ha...
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Radiation Oncologist at University of Washington School of Medicine
There is a significant risk of neuraxis disseminat...
There is a significant risk of neuraxis disseminat...