How do you treat endometrial cancer in the setting of a pCR after neoadjuvant chemotherapy?

Female in her 60s who had presented originally with well-differentiated endometrioid adeno clinically and radiographically involving bilateral parametria. She was felt to not be a surgical candidate upfront, and thus received 3-4 cycles chemotherapy. TAH/BSO showed no residual carcinoma. Would you recommend treatment based on initial stage? If so, would you recommend EBRT or brachytherapy?

Answer from: Radiation Oncologist at Community Practice

There is no data to guide. I would favor pelvic RT based on initial stage IIIB disease. We, at our institution, usually treat these patients with neoadjuvant chemo RT followed by surgery.https://www.ncbi.nlm.nih.gov/pubmed/25218303

Comments

Radiation Oncologist at BC Cancer - Vancouver
How do you decide the radiotherapy volumes and n...

Radiation Oncologist at Varian Medical Systems/Allegheny health network
If undissected involved node, would consider for b...

Please select the option that best describes you:

How do you treat endometrial cancer in the setting of a pCR after neoadjuvant chemotherapy?

Related Questions