How do you treat locally advanced, operable, Siewert 3 GE junction adenocarcinomas?
Answer from: Radiation Oncologist at Academic Institution
This remains an area of controversy, but perhaps not as controversial as Siewert type II tumors. Siewert type III tumors are staged as gastric cancers in the AJCC 8th edition. In addition, they are more histologically similar to gastric cancer and have patterns of nodal spread like gastr...
Answer from: Radiation Oncologist at Academic Institution
Bryan -
No one else is answering, so I'll give your question a go. If I recall, the Siewart-Stein classification looks at distance from the GE-junction with a 3 being pretty much firmly within the stomach. GE Junction can be treated with MAGIC chemotherapy and surgery or neoadjuvant chemoradiation ...
Answer from: Medical Oncologist at Community Practice
Siewert type III lesions - subcardial carcinoma with the tumor epicenter between 2 cm and 5 cm below the esophagogastric junction, which infiltrates the esophagogastric junction and lower esophagus from below - are considered gastric cancers. Surgical treatment follows general oncology princip...