How do you treat unresectable pancreatic adenocarcinoma invading into the duodenum?

No, 54Gy did not improve survival in the LAP-07 trial, so it is definitively not a definitive dose.

I would give 75Gy in 25 fx (100Gy BED) with capectabine. We have published how we do this in multiple papers, but essentially a 5mm duodenal PRV is carved out of the PTV75 so that there is a gradient...