How soon after EBRT would you consider salvage brachytherapy for biopsy confirmed local recurrence of prostate cancer?  

In general, salvage re-irradiation should only be performed in the setting of biopsy-proven recurrent disease. The definition of a biopsy-proven disease post an initial course of prostate radiation would be histologic evidence of a recurrence with gradable disease that could be classified with a Gle...