How would a focus of anaplastic carcinoma change your approach to adjuvant therapy for a premenopausal patient with stage IC mucinous borderline tumor of the ovary?  

I would recommend complete surgical staging; the key is whether or not the woman has disease outside of the ovary. Although we assume mucinous tumors are unlikely to spread via LN, there is new information about the type of mucinous cancers and that risk. The key is the surgical stage. If she i...