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Rheumatology • Pediatric Rheumatology
How would you approach management of a patient with sJIA that was previously well controlled on tocilizumab but is now having ongoing joint disease activity?
Patient has had intolerance to methotrexate and leflunomide in the past.
Answer from: at Academic Institution
Not sure what specifically was the intolerance to methotrexate; I personally only give it subcutaneously (more effective, bypass liver first from GI tract, better and more consistently absorbed, less GI side effects). I really like methotrexate with IL-1 blockade, as a subset of kids with sJIA go on...
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