How would you approach osteoporosis management in a patient who fractures while on denosumab therapy?
Would you consider keeping the patient on denosumab or would switch to an anabolic agent?
Answer from: at Academic Institution
This is a scenario that we run into at times and is very difficult with data suggesting a decline in BMD after discontinuation of denosumab as well as data from DATA-Switch trial from 2015 revealed that switching from denosumab to teriparatide resulted in progressive or transient bone loss. I w...