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How would you approach patients receiving neoadjuvant pembrolizumab (SWOG 1801) for melanoma with no response to systemic treatment?  

The SWOG 1801 trial showed improved event-free survival (EFS) in patients receiving neoadjuvant pembrolizumab followed by 15 cycles of adjuvant pembrolizumab after surgery. Do we need to consider changing pembrolizumab in the adjuvant setting if the patient does not respond to neoadjuvant treatment?



Answer from: Medical Oncologist at Academic Institution
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