How would you approach the use of JAK inhibitors in a patient with stable RA who is now starting treatment for pulmonary MAC infection?
Patient previously failed abatacept and Rituximab.
Answer from: at Academic Institution
Unfortunately, I would stop the JAK inhibitors, particularly in the induction antibiotic phase. Maybe treating the MAC may improve the inflammation overall and the arthritis. Once a month or 2 of antibiotics you can consider a trial of restart the JAK and see how the lungs do.