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Topics:
Medical Oncology • Myeloma
How would you decide on VRd vs DRd for initial management of transplant ineligible multiple myeloma?
Are there specific patient groups where you would choose one over the other?
Are the cost differences significant enough to dissuade you from choosing one over another?
Answer from: Medical Oncologist at Academic Institution
Both VRd and DRd are reasonable induction regimens for newly diagnosed transplant ineligible patients. DRd has the most direct evidence, as there is a phase III study (MAIA, Facon et al., NEJM, 2019) comparing DRd to Rd with both arms including treatment until progression in a transplant ineligible ...
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