How would you manage a patient with acquired von Willebrand disease who requires DAPT for arterial disease?
Answer from: at Academic Institution
Acquired vWF has many causes: lymphoproliferative disorders; MPN; autoimmune disorders; high flow disorders (Heyde syndrome) and drugs. Treating the underlying disorders would be the safest strategy because DAPT is going to cause bleeding per se in some patients and removing a second cause for bleed...