Hemostasis   

Questions discussed in this category


Assume the patient has infrequent bleeding events every few years, with use of FIX replacement for acute bleeds only.

Is there a factor XI goal that you target? Would you consider FVIIa products instead?

E.g. Normal F8, VWF activity ~50%, VWF antigen ~100%, ratio 0.5 sent in a patient with positive bleeding history Is there any clinical significance t...

Patient with high titer acquired FVIII inhibitor with no causative etiology.  Bleeding is well-controlled on emicizumab, but inhibitor has failed...

Have you used anticoagulants other than coumadin? Or is that the only appropriate agent given monitoring is based on PT/INR?

The use of anti-fibrinolytics is typically contraindicated in DIC, but does it have benefit in DIC states characterized by hyperfibrinolysis?

In a patient with severe factor XII deficiency with a baseline prolonged PTT, what is the best method to monitor their ACT or heparin levels when on c...

Especially in a patient without hemophilia or thrombosis history?

How would you treat metastatic, unresectable, solitary fibrous tumor in a patient with mild hemophilia A? Each anti-VEGF medication comes with a warni...


Papers discussed in this category


Thromb. Haemost.,

Journal of thrombosis and haemostasis : JTH, 2013-04-10

J Thromb Haemost, 2009 Aug 19

Clin Appl Thromb Hemost, 2018 Jun 19

Lancet (London, England), 2010-07-03

J Intensive Care, 2014 Feb 20

Haematologica, 2019 Oct 17

J Thromb Haemost,

Blood, 2016-07-14

Blood, 2016 Sep 26

Hematology. American Society of Hematology. Education Program, 2015