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What is the best way to monitor intraoperative heparin use in a patient with factor XII deficiency?
In a patient with severe factor XII deficiency with a baseline prolonged PTT, what is the best method to monitor their ACT or heparin levels when on cardiopulmonary bypass?
Answer from: at Academic Institution
Generally, the baseline ACT may or may not be prolonged, so one should be obtained pre-operatively. The surest way to monitor is with the heparin anti-Xa assay.
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