How would you manage a patient with recurrent granulosa tumor following secondary, R0 cytoreduction, and negative inhibins postoperatively?
Primary, R0 debulking in 2019, stage IA. Low volume recurrence, now again optimally cytoreduced.
Answer from: at Academic Institution
If inhibin was a useful marker for recurrence, I think it is acceptable to observe without further therapy, particularly if time to recurrence was prolonged. However, adjuvant therapy with paclitaxel/carboplatin would also be a good option.